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KMID : 0380620210530010046
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Korean Journal of Food Science and Technology
2021 Volume.53 No. 1 p.46 ~ p.54
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Functional screening of Asparagus officinalis L. stem and root extracts
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Han Joon-Hee
Hong Min
Lee Jae-Hak
Choi Da-Hye
Lee Sun-Yeop
Kwon Tae-Hyung
Lee Jae-Hee
Lee Yong-Jin
Yu Keun-Hyung
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Abstract
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The biological activities of non-edible extracts of asparagus stems and roots were investigated using hot water and ethanol. The highest contents of rutin and total polyphenol were 31.74 mg/g and 20.14 mg GAE/g, respectively, in the stem hot water extract. ABTS and DPPH radical scavenging activities were 541.1±21.0 and 649.5±6.6 μg/mL, respectively, in stem hot water extract. All extracts were non-cytotoxic in HepG2 cells, but 200 μg/mL stem extracts tended to decrease the viability of RAW 264.7 cells. The highest xanthine oxidase inhibitory activity was 43.68% in the root hot water extract at 200 μg/mL. The expression level of MMP-9 was significantly decreased in the asparagus extracts. The highest GGT, AST, and LDH activities showed a concentration-dependent decrease in the stem ethanol extract. In conclusion, the presence of bioactive substances in the non-edible extracts of asparagus was confirmed for the development of extracts with antioxidant, hepatoprotective and anti-gout activities.
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KEYWORD
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anti-gout, antioxidant, asparagus, hepatoprotective, rutin
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